α-Actinin belongs to the spectrin family of cytoskeletal proteins. α-Actinin is necessary for the attachment of actin filaments to the Z-lines in skeletal muscle cells, and to the dense bodies in smooth muscle cells. The functional protein is an anti-parallel dimer, which cross-links the thin filaments in adjacent sarcomeres, and therefore coordinated contractions between sarcomeres in the horizontal axis.
a-actinin (4A12) Mouse mAb
£118.40 – £198.40 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 87 |
| Applications | IHC |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | IHC 1:100-200 |
| Clonality | Monoclonal |
