Autophagy is generally activated by conditions of nutrient deprivation but has also been associated with a number of physiological processes including development, differentiation, neurodegeneration, infection, and cancer. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
ATG5 (3C7) Mouse mAb
£118.40 – £198.40 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 9494 |
| Applications | IHC, WB |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | WB 1:5, 000-10, 000 IHC 1:100-200 |
| Clonality | Monoclonal |
