The molecular machinery of autophagy was largely discovered in yeast and referred to as autophagy-related (Atg) genes. Formation of the autophagosome involves a ubiquitin-like conjugation system in which Atg12 is covalently bound to Atg5 and targeted to autophagosome vesicles. This conjugation reaction is mediated by the ubiquitin E1-like enzyme Atg7 and the E2-like enzyme Atg10.
Size | 50μL, 100μL |
---|---|
Gene ID | 10533 |
Applications | IHC |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | IHC 1:100-200 |
Clonality | Monoclonal |