Bone morphogenetic protein-2 (BMP-2) is a member of the transforming growth factor-beta (TGFB) superfamily. BMP2 is synthesized as a 60 kDa precursor that is processed in the secretory pathway to a small 18 kDa monomer; 2 monomers then associate to form the active 30 kDa homodimer,which binds to its receptor. There is also a 40-45 kDa form of BMP2,as an amino-terminal propeptide. BMP2 can induce bone formation and regeneration during early embryonic development. It is involved in the hedgehog pathway,TGF beta signaling pathway,and cytokine-cytokine receptor interaction.
BMP2 Monoclonal Antibody
£192.00 – £399.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P12643, P21274, P49001 |
| Applications | IHC |
| Reactivity | Rat |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Cardiovascular, Signal Transduction, Stem Cells |
| Concentration | 2.65 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Recombinant protein corresponding to Mouse BMP2 |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Dilution | IHC 1:200-1:800 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
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