The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death.
c-Fos Monoclonal Antibody
£192.00 – £399.00 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P01100, P01101, P12841 |
| Applications | WB, IHC, IF |
| Reactivity | Human, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Epigenetics and Nuclear Signaling, Neuroscience |
| Concentration | 0.97 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | KLH conjugated Synthetic peptide corresponding to Mouse c-FOS |
| Buffer | PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4 |
| Purification Method | Affinity purification |
| Dilution | WB 1:500-1:2000, IHC 1:500-1:2000, IF 1:200-1:1000 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
| Citation Link 1 | https://www.sciencedirect.com/science/article/pii/S0024320519305582 |
| Citation Link 2 | |
| Citation Link 3 | |
| Citation Link 4 | |
| Citation Link 5 |
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