Fagus Antibody Services

Caspase 3 Rabbit pAb

£118.40£248.00 excluding VAT

CASP3 (Caspase 3) is a Protein Coding gene. Diseases associated with CASP3 include Lung Cancer and Nervous System Cancer. Among its related pathways are AGE/RAGE pathway and p75 NTR receptor-mediated signalling. The protein encoded by CASP3 is a cysteine-aspartic acid protease that plays a central role in the execution-phase of cell apoptosis. The encoded protein cleaves and inactivates poly(ADP-ribose) polymerase while it cleaves and activates sterol regulatory element binding proteins as well as caspases 6, 7, and 9. This protein itself is processed by caspases 8, 9, and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer’s disease.

Size

50μL, 100μL

Gene ID

836

Applications

ELISA, WB

Reactivity

Human 1, Mouse, Rat

Host

Rabbit

Isotype
Concentration

1mg/ml

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Dilution
Clonality

Polyclonal

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