Fagus Antibody Services

CD68 Mouse mAb

£118.40£198.40 excluding VAT

SKU FAS-1050-MA Category

The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells.

Size

50μL, 100μL

Gene ID

968

Applications

IHC

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG1

Concentration

1mg/ml

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Dilution

IHC 1:200

Clonality

Monoclonal

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