Fagus Antibody Services

CK-19 Monoclonal Antibody

£192.00£399.00 excluding VAT

The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. KRT19,one of type I keratins,is specifically expressed in the periderm,the transiently superficial layer that envelopes the developing epidermis. Due to its high sensitivity,KRT19 is the most used marker for detection of tumor cells disseminated in lymph nodes,peripheral blood,and bone marrow of breast cancer patients. This antibody,generated against full length KRT19 protein,also recognizes KRT17,another type I keratin homologous to KRT19. KRT17 is used as a marker for trauma.

Size

120μL, 200μL

Swissprot

P19001, Q63279

Applications

IHC

Reactivity

Mouse, Rat

Host

Mouse

Isotype

IgG

Research Areas

Cancer, Signal Transduction

Concentration

1.1 mg/mL

Storage

Store at -20°C. Avoid freeze / thaw cycles.

Immunogen

KLH conjugated Synthetic peptide corresponding to Mouse Cytokeratin 19

Buffer

PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method

Affinity purification

Dilution

IHC 1:500-1:2000

Conjugation

Unconjugated

Clonality

Monoclonal

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