Fagus Antibody Services

Cleaved-CD97β (S531) Rabbit pAb

£118.40£248.00 excluding VAT

ADGRE5 (adhesion G protein-coupled receptor E5) encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of ADGRE5 may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for ADGRE5. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.

Size

50μL, 100μL

Gene ID

976

Applications

ELISA, WB

Reactivity

Human 1

Host

Rabbit

Isotype
Concentration

1mg/ml

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Dilution
Clonality

Polyclonal

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