CRY1 encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. CRY1 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in CRY1 have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness.
CRY1 Rabbit pAb
£118.40 – £248.00 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 1407 |
| Applications | ELISA, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
