The G-Patch Domain Containing 8 encoded by GPATCH8 contains an RNA-processing domain, a zinc finger domain, a lysine-rich region and a serine-rich region. A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms. GPATCH8 (G-Patch Domain Containing 8) is a Protein Coding gene. Diseases associated with GPATCH8 include Hyperuricemia.