The protein encoded by GTSE1 is only expressed in the S and G2 phases of the cell cycle, where it colocalizes with cytoplasmic tubulin and microtubules. In response to DNA damage, the encoded protein accumulates in the nucleus and binds the tumor suppressor protein p53, shuttling it out of the nucleus and repressing its ability to induce apoptosis. GTSE1 (G2 And S-Phase Expressed 1) is a Protein Coding gene. Among its related pathways are Regulation of PLK1 Activity at G2/M Transition and CDK-mediated phosphorylation and removal of Cdc6.
Size | 50μL, 100μL |
---|---|
Gene ID | 51512 |
Applications | ELISA, WB |
Reactivity | Human 1 |
Host | Rabbit |
Isotype | |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | |
Clonality | Polyclonal |
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