HJURP (Holliday Junction Recognition Protein) is a Protein Coding gene. Diseases associated with HJURP include Fibrillary Astrocytoma. Among its related pathways are DNA Damage and Chromosome Maintenance. Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.
Size | 50μL, 100μL |
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Gene ID | 55355 |
Applications | ELISA, WB |
Reactivity | Human 1 |
Host | Rabbit |
Isotype | |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | |
Clonality | Polyclonal |