Fagus Antibody Services

JAK2/3 (Phospho-Tyr966/939) Antibody

£118.40£248.00 excluding VAT

JAK2 (Janus kinase 2) belongs to the emerging family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK2. JAK2 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription.

Size

50μL, 100μL

Gene ID

1132/1124

Applications

ELISA, WB

Reactivity

Human 1, Mouse, Rat

Host

Rabbit

Isotype
Concentration

1mg/ml

Storage

PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Dilution
Clonality

Polyclonal

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