JAK2 (Janus kinase 2) belongs to the emerging family of non-receptor Janus tyrosine kinases, which regulate a spectrum of cellular functions downstream of activated cytokine receptors in the lympho-hematopoietic system. Immunological stimuli, such as interferons and cytokines, induce recruitment of Stat transcription factors to cytokine receptor-associated JAK2. JAK2 then phosphorylates proximal Stat factors, which subsequently dimerize, translocate to the nucleus and bind to cis elements upstream of target gene promoters to regulate transcription.
JAK2 Rabbit pAb
£118.40 – £248.00 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 3717 |
| Applications | IHC |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
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Polyclonal Antibody
Cleaved-Plasminogen HC A short form (V98) Rabbit pAb
£76.00 – £248.00 excluding VAT