Melan-A is a melanocyte differentiation antigen,recognized by autologous cytotoxic T lymphocytes. Melan-A is also called MART-1 (melanoma antigen recognized by T cells). The Melan-A/MART-1 gene encodes this protein,20-22 kDa,associated with endoplasmic reticulum and melanosomes. The function of the protein is unknown. Melan-A,isolated as a melanoma-specific antigen,is a transmembrane protein,which is expressed in skin,retina and the majority of cultured melanocytes as well as in melanomas. Melan A is expressed in more than 85% of melanomas.
Cancer, Immunology, Tags and Cell Markers
Store at -20°C. Avoid freeze / thaw cycles.
Synthetic peptide of human MLANA
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Antigen affinity purification
IHC 1:40-1:250, ELISA 1:5000-1:10000
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