Melan-A is a melanocyte differentiation antigen,recognized by autologous cytotoxic T lymphocytes. Melan-A is also called MART-1 (melanoma antigen recognized by T cells). The Melan-A/MART-1 gene encodes this protein,20-22 kDa,associated with endoplasmic reticulum and melanosomes. The function of the protein is unknown. Melan-A,isolated as a melanoma-specific antigen,is a transmembrane protein,which is expressed in skin,retina and the majority of cultured melanocytes as well as in melanomas. Melan A is expressed in more than 85% of melanomas.
MLANA Polyclonal Antibody
£192.00 – £319.20 excluding VAT
SKU
FAS-19522-A
Category Polyclonal Antibody
Tags Antigen LB39 AA, Antigen LB39-AA, Antigen SK29 AA, Antigen SK29-AA, MAR1, MART 1, MART-1, MART1, Melan A, Melan A protein, Melanoma antigen recognized by T cells 1, Melanoma antigen recognized by T-cells 1, MLAN A, MLANA, OTTHUMP00000021036, OTTHUMP00000021037, OTTHUMP00000021038, Protein Melan-A
Size | 120μL, 200μL |
---|---|
Swissprot | Q16655 |
Applications | ELISA, IHC |
Reactivity | Human 1 |
Host | Rabbit |
Isotype | IgG |
Research Areas | Cancer, Immunology, Tags and Cell Markers |
Concentration | 1 mg/mL |
Storage | Store at -20°C. Avoid freeze / thaw cycles. |
Immunogen | Synthetic peptide of human MLANA |
Buffer | PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method | Antigen affinity purification |
Dilution | IHC 1:40-1:250, ELISA 1:5000-1:10000 |
Conjugation | Unconjugated |
Clonality | Polyclonal |
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