Fagus Antibody Services

MMP9 Monoclonal Antibody

£192.00£399.00 excluding VAT

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow, and murine studies suggest a role in tumor-associated tissue remodeling.

Size

120μL, 200μL

Swissprot

P14780, P50282, P41245

Applications

WB

Reactivity

Human, Mouse, Rat

Host

Mouse

Isotype

IgG

Research Areas

Cancer, Cell Biology, Cardiovascular, Signal Transduction

Concentration

3.5 mg/mL

Storage

Store at -20°C. Avoid freeze / thaw cycles.

Immunogen

Recombinant protein corresponding to Mouse MMP9

Buffer

PBS with 0.02% sodium azide, 1% BSA and 50% glycerol, pH7.4

Purification Method

Affinity purification

Dilution

WB 1:500-1:2000

Conjugation

Unconjugated

Clonality

Monoclonal

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