Muscle myosin is a hexameric protein that consists of 2 heavy chain subunits (MHC), 2 alkali light chain subunits (MLC) and 2 regulatory light chain subunits (MLC-2). Cardiac MHC exists as two isoforms in humans, alpha-cardiac MHC and beta-cardiac MHC. These two isoforms are expressed in different amounts in the human heart. During normal physiology, beta-cardiac MHC is the predominant form, with the alpha-isoform contributing around only 7% of the total MHC. Mutations of the MHC genes are associated with several different dilated and hypertrophic cardiomyopathies.
Myosin Heavy Chain Mouse mAb
£118.40 – £198.40 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 4619 |
| Applications | IF, IHC |
| Reactivity | Fruitfly, Human, Mouse, Nematode, Rat |
| Host | Mouse |
| Isotype | IgG1 |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | IHC 1:200 IF 1:100 |
| Clonality | Monoclonal |
