NBR1 protein is known for its encoding gene proximity to the BRCA1 tumor suppressor gene. N-terminal Phox and Bem1p (PB1) domains of NBR1 mediate its interaction with muscle specific titin kinase and scaffolding protein p62. NBR1 plays a role in autophagy by facilitating the autophagosomal degradation of ubiquitinated proteins independently and also in concert with p62.
Size | 50μL, 100μL |
---|---|
Gene ID | 4077 |
Applications | IHC |
Reactivity | Human, Mouse, Rat |
Host | Mouse |
Isotype | IgG1 |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | IHC 1:100-200 |
Clonality | Monoclonal |