NOBOX (NOBOX Oogenesis Homeobox) is a Protein Coding gene. Diseases associated with NOBOX include Premature Ovarian Failure 5 and Amenorrhea. GO annotations related to NOBOX include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. This homeobox gene encodes a transcription factor that is thought to play a role in oogenesis. In mice, it is essential for folliculogenesis and regulation of oocyte-specific genes. Defects in NOBOX result in premature ovarian failure type 5.