NTHL1 encoded by this gene is a DNA N-glycosylase of the endonuclease III family. Like a similar protein in E. coli, the encoded protein has DNA glycosylase activity on DNA substrates containing oxidized pyrimidine residues and has apurinic/apyrimidinic lyase activity. NTHL1 (Nth Like DNA Glycosylase 1) is a Protein Coding gene. Diseases associated with NTHL1 include Familial Adenomatous Polyposis 3 and Periampullary Adenoma. Among its related pathways are DNA damage_Role of Brca1 and Brca2 in DNA repair and Telomere C-strand (Lagging Strand) Synthesis.
Size | 50μL, 100μL |
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Gene ID | 4913 |
Applications | ELISA, WB |
Reactivity | Human 1, Mouse |
Host | Rabbit |
Isotype | |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | |
Clonality | Polyclonal |