The protein encoded by PTH1R (parathyroid hormone 1 receptor) is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen’s metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for PTH1R.
Parathyroid hormone/parathyroid hormone-related peptide receptor Rabbit pAb
£118.40 – £248.00 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 5745 |
| Applications | ELISA, IHC, WB |
| Reactivity | Human 1 |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
