This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3′-5′ exonuclease and 3′-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
PCNA Monoclonal Antibody
£192.00 – £319.20 excluding VAT
| Size | 120μL, 200μL |
|---|---|
| Swissprot | P12004 |
| Applications | IF, IHC-p, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Mouse |
| Isotype | IgG |
| Research Areas | Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Tags and Cell Markers |
| Concentration | 1 mg/mL |
| Storage | Store at -20°C. Avoid freeze / thaw cycles. |
| Immunogen | Synthetic Peptide |
| Buffer | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Purification Method | Protein A purification |
| Dilution | WB 1:5000-1:10000, IHC 1:100-1:300, IF 1:100-1:300 |
| Conjugation | Unconjugated |
| Clonality | Monoclonal |
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