PERK is also named as PEK, EIF2AK3 (Eukaryotic translation initiation factor 2-alpha kinase 3) and belongs to the GCN2 subfamily. It acts potentially as a metabolic sensor in the insulin-secreting beta-cells to modulate the trafficking and quality control of proinsulin in the ER relative to the physiological demands for circulating insulin.PERK and EIF2AK4 also have a functional role on regulating translation under non-stressed conditions, apart from their long established roles as stress kinases.
PERK Rabbit pAb
£118.40 – £248.00 excluding VAT
| Size | 50μL, 100μL |
|---|---|
| Gene ID | 9451 |
| Applications | ELISA, IHC, WB |
| Reactivity | Human 1, Mouse, Rat |
| Host | Rabbit |
| Isotype | |
| Concentration | 1mg/ml |
| Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
| Dilution | |
| Clonality | Polyclonal |
