cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits.
PKA Iα reg Rabbit pAb
£118.40 – £248.00 excluding VAT
Size | 50μL, 100μL |
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Gene ID | 5573 |
Applications | ELISA, IF, IHC, WB |
Reactivity | Human 1, Mouse, Rat |
Host | Rabbit |
Isotype | |
Concentration | 1mg/ml |
Storage | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles. |
Dilution | |
Clonality | Polyclonal |