Thymic stromal lymphopoietin (TSLP) is a protein belonging to the cytokine family, contains 140 amino acids. It is known to play an important role in the maturation of T cell populations through activation of antigen presenting cells. TSLP induces the release of T-cell-attracting chemokines from monocytes and, in particular, enhances the maturation of CD11c+ dendritic cells. It can induce allergic inflammation by directly activating mast cells. TSLP is produced mainly by non-hematopoietic cells such as fibroblasts, epithelial cells and different types of stromal or stromal-like cells. These cells are located in regions where TSLP activity is required.
Recombinant Cynomolgus Thymic Stromal Lymphopoietin/TSLP (C-6His)
£104.00 – £314.40 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | Active protein |
| Activity | Immobilized Mouse TSLPR-Fc(Cat#PKSM041158) at 10μg/ml (100 μl/well) can bind Biotinylated Cynomolgus TSLP-His(Cat#PKSQ050102). The ED50 of Cynomolgus TSLP-His(Cat#PKSQ050102)is 3.2ug/ml . |
| Protein Construction | Recombinant Cynomolgus Thymic Stromal Lymphopoietin is produced by our E.coli expression system and the target gene encoding Tyr29-Gln159(Glu37Gln) is expressed with a 6His tag at the C-terminus. |
| Sequence | Tyr29-Gln159(Glu37Gln) |
| Fusion Tag | C-6His |
| Accession | XP_005557555.1 |
| Species | Cynomolgus |
| Expressed Host | E.coli |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 16.2 kDa |
| AP Mol Mass | 16 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 500mM NaCl, pH 7.4. |
| Research Areas | |
| Reconstitution | Please refer to the printed manual for detailed information. |
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