Fagus Antibody Services

Recombinant Human 4-1BB/TNFRSF9 Protein (Fc & His Tag)(Active)

£98.40£250.00 excluding VAT

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells; but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL; and possibly active during T cell activation.

Size

10µg, 50µg

Active Protein

Active protein

Activity

Immobilized Human 4-1BBL-His(Cat: PKSH032023) at 0.03μg/ml(100 μl/well) can bind Human 4-1BB-Fc. The ED50 of Human 4-1BB-Fc is 7.22 ug/ml .

Protein Construction

Recombinant Human 4-1BB ligand receptor is produced by our Mammalian expression system and the target gene encoding Leu24-Gln186 is expressed with a Fc; 6His tag at the C-terminus. 

Sequence

Leu24-Gln186

Fusion Tag

C-Fc-6His

Accession

Q07011

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

44.0 kDa

AP Mol Mass

55-75 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS pH7.4.

Research Areas

Cell biology, Cancer, immunology, Stem cells

Reconstitution

Please refer to the printed manual for detailed information.

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