Fagus Antibody Services

Recombinant Human Activin RIIA/ACVR2A Protein (Fc & His Tag)(Active)

£49.60£178.00 excluding VAT

Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins; composed of a ligand-binding extracellular domain with cysteine-rich region; a transmembrane domain; and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding; resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.


10µg, 50µg

Active Protein

Active protein


Immobilized Human INHBC-His(Cat: PKSH032587) at 0.8μg/ml(100 μl/well) can bind Human ACVR2A-Fc-6His. The ED50 of Human ACVR2A-Fc-6His is 6.73 ug/ml.

Protein Construction

Recombinant Human Activin Receptor Type-2A is produced by our Mammalian expression system and the target gene encoding Ala20-Pro134 is expressed with a Fc; 6His tag at the C-terminus.



Fusion Tag






Expressed Host

Human Cells


This product is provided as lyophilized powder which is shipped with ice packs.


> 95 % as determined by reducing SDS-PAGE.


< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

41.2 kDa

AP Mol Mass

36 kDa


Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Research Areas

Signal Transduction, Cancer, metabolism, Stem cells


Please refer to the printed manual for detailed information.

Related Product