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Recombinant Human Alpha-Synuclein/SNCA Protein (His Tag)

£49.60 – £129.00 excluding VAT

SKU FAS-033254-P Category Tag

Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1; Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition; SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson’s Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Human alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed with a 6His tag at the N-terminus.
Sequence

Met 1-Ala140
Fusion Tag

N-6His
Accession

P37840
Species

Human
Expressed Host

E.coli
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 90 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

16.7 kDa
AP Mol Mass

18 kDa
Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Research Areas

Neuroscience
Reconstitution

Please refer to the printed manual for detailed information.

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