Fagus Antibody Services

Recombinant Human APOM Protein (Fc Tag)

£536.00£670.00 excluding VAT

ApoM (apolipoprotein M) is an apolipoprotein and member of the lipocalin protein family. The lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They have an eight-stranded; antiparallel; symmetrical _-barrel fold; which is in essence a beta sheet which has been rolled into a cylindrical shape. Inside this barrel is located a ligand binding site. They transport small hydrophobic molecules such as steroids; bilins; retinoids; and lipids. Lipocalins have been associated with many biological processes; among them immune response; pheromone transport; biological prostaglandin synthesis; retinoid binding; and cancer cell interactions. Lipocalins are comparatively small in size; and are thus less complicated to study as opposed to large; bulky proteins. They can also bind to various ligands for different biological purposes. ApoM is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. ApoM is involved in lipid transport and can bind sphingosine-1-phosphate; myristic acid; palmitic acid and stearic acid; retinol; all-trans-retinoic acid and 9-cis-retinoic acid.

Size

50µg

Active Protein
Activity
Protein Construction

A DNA sequence encoding the human APOM (O95445) (Met 1-Asn 188) was fused with the Fc region of human IgG1 at the C-terminus.

Sequence

Met 1-Asn 188

Fusion Tag

C-Fc

Accession

O95445

Species

Human

Expressed Host

HEK293 Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 85 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

45.6 kDa

AP Mol Mass

50 kDa

Formulation

Lyophilized from sterile PBS, pH 7.4

Research Areas

Signal Transduction, Cardiovascular, Cancer, metabolism

Reconstitution

Please refer to the printed manual for detailed information.

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