3-Hydroxybutyrate Dehydrogenase Type 2 belongs to the short-chain dehydrogenases/reductases (SDR) family. 3-Hydroxybutyrate Dehydrogenase Type 2 may play an important role in the peripheral utilization of 3-hydroxybutyrate. The cytoplasmic localization with its high ratio of oxidized NAD+, the NAD+ dependence and the kinetic parameters of 3-Hydroxybutyrate Dehydrogenase Type 2 make it suitable to conbert high levels of circulating 3-hydroxybutyrate into acetoacetate.
Recombinant Human BDH2 Protein (His Tag)
£178.40 – £593.00 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Human 3-Hydroxybutyrate Dehydrogenase Type 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu245 is expressed with a 6His tag at the N-terminus. |
| Sequence | Met 1-Leu245 |
| Fusion Tag | N-6His |
| Accession | Q9BUT1 |
| Species | Human |
| Expressed Host | E.coli |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 28.9 kDa |
| AP Mol Mass | 30 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, pH 8.0. |
| Research Areas | Signal Transduction, Cell biology, Cardiovascular, Cancer, metabolism |
| Reconstitution | Not Applicable |
