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Recombinant Human BDNF protein(His tag)

£152.00 – £276.00 excluding VAT

SKU FAS-500073-P Category Tag

Important signaling molecule that activates signaling cascades downstream of NTRK2.During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.

Size

20µg, 50µg
Active Protein
Activity
Protein Construction

A DNA sequence encoding theHuman BDNF protein (P23560) (Met1-Arg247) was expressed with a C-His.
Sequence

Met1-Arg247
Fusion Tag

C-His
Accession

P23560
Species

Human
Expressed Host

HEK293 Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 85 % as determined by reducing SDS-PAGE.
Endotoxin

Please contact us for more information.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

26 kDa
AP Mol Mass

26 kDa
Formulation

Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.
Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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