Fagus Antibody Services

Recombinant Human BMPR2 protein(His tag)

£38.40£92.00 excluding VAT

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP7, BMP2 and, less efficiently, BMP4. Binding is weak but enhanced by the presence of type I receptors for BMPs. Mediates induction of adipogenesis by GDF6.

Size

20µg, 100µg

Active Protein
Activity
Protein Construction

A DNA sequence encoding theHuman BMPR2 protein (Q13873) (Ser27-Thr150) was expressed with a N-His.

Sequence

Ser27-Thr150

Fusion Tag

N-His

Accession

Q13873

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 85 % as determined by reducing SDS-PAGE.

Endotoxin

Please contact us for more information.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

26 kDa

AP Mol Mass

35 kDa

Formulation

Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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