Butyrophilin Subfamily 1 Member A1 (BTN1A1) is the major protein associated with fat droplets in the milk. It belongs the immunoglobulin superfamily. BTN1A1 acts as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. It is localized to the major histocompatibility complex (MHC) class I region of 6p. It may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families. It is shown that BTN1A1 inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Recombinant Human Butyrophilin Subfamily 1 Member A1/BTN1A1 (C-6His-Avi) Biotinylated
£273.60 – £739.20 excluding VAT
Size | 20µg, 100µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Biotinylated Recombinant Human Butyrophilin Subfamily 1 Member A1 is produced by our Mammalian expression system and the target gene encoding Ala27-Arg242 is expressed with a 6His, Avi tag at the C-terminus. |
Sequence | Ala27-Arg242 |
Fusion Tag | C-6His-Avi |
Accession | Q13410 |
Species | Human |
Expressed Host | Human Cells |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 26.8 kDa |
AP Mol Mass | 35-40 kDa |
Formulation | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Research Areas | Cardiovascular |
Reconstitution | Please refer to the printed manual for detailed information. |
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