Catalase (CAT) is a member of the catalase family. It exists as a homotetramer that occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase is localized in the peroxisome. Catalase promotes growth of cells including T-cells; B-cells; myeloid leukemia cells; melanoma cells; mastocytoma cells; and normal and transformed fibroblast cells. Defects in CAT are the cause of acatalasemia which is characterized by absence of catalase activity in red cells and is associated with ulcerating oral lesions.
Recombinant Human Catalase/CAT Protein
£178.40 – £593.00 excluding VAT
| Size | 10µg, 50µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Recombinant Human Catalase is produced by our E.coli expression system and the target gene encoding Ala2-Leu527 is expressed. |
| Sequence | Ala2-Leu527 |
| Fusion Tag | |
| Accession | P04040 |
| Species | Human |
| Expressed Host | E.coli |
| Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
| Purity | > 85 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
| Mol Mass | 59.7 kDa |
| AP Mol Mass | 60 kDa |
| Formulation | Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4. |
| Research Areas | Signal Transduction, Tags & Cell Markers, Cardiovascular, Cancer, metabolism |
| Reconstitution | Not Applicable |
