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Recombinant Human CCD5L Protein (His Tag)

£585.60 – £732.00 excluding VAT

SKU FAS-031429-P Category Tag

CD5L, also known as CD5 antigen-like, is a soluble protein belonging to group B of the scavenger receptor cysteine-rich (SRCR) superfamily and contains three SRCR domains. It is a secreted glycoprotein and expressed by macrophages presentin lymphoid tissues (spleen, lymph node, thymus, and bone marrow). It binds to myelomonocytic and lymphoid cells and may play an important role in the regulation of the innate and adaptive immune systems. CD5L functions as a pattern recognition molecule by binding both lipoteichoic acid (LTA) on Gram positive and lipopolysaccharide (LPS) on Gram negative bacteria. and the SRCR domain 1 of CD5L retains both the LPS and LTA binding activities. In addtion, it is revealed that CD5L seems to play a role as an inhibitor of apoptosis.

Size

100µg
Active Protein
Activity
Protein Construction

A DNA sequence encoding the human CD5L (NP_005885.1) (Met 1-Gly 347) with a C-terminal polyhistidine tag was expressed.
Sequence

Met 1-Gly 347
Fusion Tag

C-His
Accession

NP_005885.1
Species

Human
Expressed Host

HEK293 Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 97 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg of the protein as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

37.5 kDa
AP Mol Mass

45 kDa
Formulation

Lyophilized from sterile PBS, pH 7.4
Research Areas

Cell biology
Reconstitution

Please refer to the printed manual for detailed information.

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