Chemokine (C-C Motif) Ligand 1 (CCL1) is a small glycoprotein secreted by activated T cells, which play a
central role during immunoregulatory and inflammaion processes. Human CCL1 has been assumed to be a
homologue of the mouse TCA3. While the two proteins share only approximately 42% amino acid sequence
identity, both chemokines contain an extra pair of cysteine residues not found in most other chemokines.
CCL1 attracts monocytes, NK cells, and immature B cells and dendritic cells by interacting with cell surface
chemokine receptor CCR8. CCL1 is identified as a potent inhibitor of HIV-1 envelope-mediated cell-cell
fusion and virus infection.
Recombinant Human CCL1/I-309 Protein
£195.20 – £532.80 excluding VAT
SKU
FAS-033809-P
Category Protein
Tag C-C Motif Chemokine 1; Small-Inducible Cytokine A1; T Lymphocyte-Secreted Protein I-309; CCL1; SCYA1
Size | 10µg, 50µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Recombinant Human C-C Motif Chemokine 1 is produced by our E.coli expression system and the target gene encoding Lys24-Lys96 is expressed. |
Sequence | Lys24-Lys96 |
Fusion Tag | |
Accession | P22362 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 8.62 kDa |
AP Mol Mass | 10 kDa |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Research Areas | immunology |
Reconstitution | Please refer to the printed manual for detailed information. |
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