Fagus Antibody Services

Recombinant HCoV-OC43 Nucleocapsid Protein

£204.00£1,780.00 excluding VAT

Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. N protein packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.

Size

50µg, 500µg

Active Protein
Activity

Test in progress

Protein Construction

Recombinant HCoV-OC43 Nucleocapsid Protein is produced by our E.coli expression system and the target gene encoding Met1-Ile448 is expressed with a 6His tag at the N-terminus.

Sequence

Met1-Ile448

Fusion Tag

N-6His

Accession

P33469

Species

HCoV

Expressed Host

E.coli

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

Please contact us for more information.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

53kDa     

AP Mol Mass

57kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM NaAc-HAc, 150mM NaCl, 5% Trehalose, pH 4.5

Research Areas

Virus related Protein

Reconstitution

Not Applicable

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