Fagus Antibody Services

Recombinant Human CD47/IAP Protein (Fc & Avi Tag)

£273.60£739.20 excluding VAT

CD47(Integrin-Associated Protein;IAP) is a 40 – 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages; neutrophils; and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin; and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution; and is reduced in expression on Rh erythrocytes.

Size

20µg, 100µg

Active Protein
Activity
Protein Construction

Biotinylated Recombinant Human CD47 is produced by our Mammalianexpression system and the target gene encoding Gln19-Pro139 is expressed with a Fc; Avi tag at the C-terminus.

Sequence

Gln19-Pro139

Fusion Tag

C-Fc-Avi

Accession

Q08722

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

42.7 kDa

AP Mol Mass

60-70 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Research Areas

Cancer, immunology

Reconstitution

Please refer to the printed manual for detailed information.

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