Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.
Size | 20µg, 100µg |
---|---|
Active Protein | Active protein |
Activity | Immunogen(E-AB-40324) |
Protein Construction | A DNA sequence encoding the Human CD59 glycoprotein protein (P13987-1) (26L-102N) was expressed with a polyhistidine tag at the N/C-terminus. |
Sequence | 26L-102N |
Fusion Tag | N-His |
Accession | P13987-1 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
Purity | > 90 % as determined by reducing SDS-PAGE. |
Endotoxin | Please contact us for more information. |
Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
Mol Mass | 10.2kDa |
AP Mol Mass | 14-16kDa |
Formulation | Lyophilized from sterile PBS, pH 7.4 |
Research Areas | |
Reconstitution | Please refer to the printed manual for detailed information. |
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