Fagus Antibody Services

Recombinant Human CD81 (N-FC)

£129.60£388.00 excluding VAT

CD81, also known as TAPA-1 and Tetraspanin-28, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. CD81 associates with a wide range of membrane proteins including CD151, TfR2, LDL R, PCSK9, Glypican 3, IFITM1, IGSF8/CD316, FPRP, and complexes of CD19-CD21. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. CD81 additionally functions as a receptor for the E2 glycoprotein of hepatitis C virus. The CD81-E2 interaction inhibits NK cell cytolytic activity, provides a co-stimulatory signal to T cells, and inhibits the maturation of plasmacytoid dendritic cells.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human CD81 antigen is produced by our Mammalian expression system and the target gene encoding Phe113-Lys201 is expressed with a Fc tag at the N-terminus.

Sequence

Phe113-Lys201

Fusion Tag

N-Fc

Accession

P60033

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

36.1 kDa

AP Mol Mass

37 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas

Microbiology, immunology

Reconstitution

Please refer to the printed manual for detailed information.

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