Fagus Antibody Services

Recombinant Human CTNNB1 Protein

£224.00£540.00 excluding VAT

SKU FAS-500056-P Category Tags , , , , ,

Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.

Size

20μg, 100μg

Active Protein
Activity
Protein Construction

A DNA sequence encoding the Human Human CTNNB1 Protein(P35222)(131-670)was expressed with a polyhistidine tag at the N-terminus.

Sequence

Met131-Tyr670

Fusion Tag

N-His

Accession

NP_001091679.1

Species

Human

Expressed Host

E.coli

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 85 % as determined by reducing SDS-PAGE.

Endotoxin

Please contact us for more information.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

59 kDa

AP Mol Mass

59 kDa

Formulation

Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% tween-80.

Research Areas

Cancer, Cardiovascular, Neuroscience, Signal Transduction

Reconstitution

Please refer to the printed manual for detailed information.

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