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Recombinant Human FAM20B/Gxk1 Protein (Fc Tag)

£684.00 – £855.00 excluding VAT

SKU FAS-030547-P Category Tag

PSG6 is a pregnancy-specific glycoprotein(PSG). PSGs are secreted proteins which are produced by the rodent and primate placenta and play a critical role in pregnancy success. The levels of PSGs are highest during the third trimester of pregnancy, a time marked by the most profound suppression of MS disease attacks. PSGs regulate T-cell function. The regulation of T-cell function during pregnancy is likely the result of significant hormonal changes and may well involve immunoregulatory proteins derived from the placenta. Pregnancy specific glycoproteins (PSGs) are the most abundant placentally derived glycoproteins in the maternal serum. PSG1, PSG6, PSG6N, and PSG11 induce dose-dependent secretion of anti-inflammatory cytokines by human monocytes. Human and murine PSGs exhibit cross-species activity.

Size

100µg
Active Protein
Activity
Protein Construction

A DNA sequence encoding the human FAM20B (NP_055679.1)(Ser31-Leu409) was expressed with the fused Fc region of human IgG1 at the N-terminus.
Sequence

Ser31-Leu409
Fusion Tag

N-Fc
Accession

NP_055679.1
Species

Human
Expressed Host

HEK293 Cells
Shipping

This product is provided as lyophilized powder which is shipped with ice packs.
Purity

> 90 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg of the protein as determined by the LAL method.
Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Mol Mass

71.4 kDa
AP Mol Mass

72.2 kDa
Formulation

Lyophilized from sterile PBS, pH 7.4
Research Areas

Signal Transduction, Tags & Cell Markers
Reconstitution

Please refer to the printed manual for detailed information.

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