Fagus Antibody Services

Recombinant Human FGL1 (C-Avi-6His) Biotinylated

£312.00£784.00 excluding VAT

Fibrinogen-like protein 1(FGL1) is also known as HP-041, Hepassocin, HFREP-1, LFIRE-1, is a liver-specific secreted protein belonging to the fibronogen superfamily, whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.

Size

20µg, 100µg

Active Protein

Active protein

Activity

Immobilized Human LAG-3-Fc(Cat#CU30) at 10μg/ml (100 μl/well) can bind  Biotinylated Human FGL1-Avi(Cat#CY21). The ED50 of Human FGL1-Avi (Cat#CY21) is 1908ng/mL.

Protein Construction

Biotinylated Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a Avi, 6His tag at the C-terminus.

Sequence

Leu23-Ile312

Fusion Tag

C-Avi-6His

Accession

Q08830

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity

> 90 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Mol Mass

36.6 kDa

AP Mol Mass

35 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 300mM NaCl, 10% Glycerol, 2mM EDTA, pH 8.0.

Research Areas

Cardiovascular

Reconstitution

Not Applicable

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