Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Recombinant Human GGCT Protein (His Tag)
£178.40 – £593.00 excluding VAT
SKU
FAS-033273-P
Category Protein
Tag Gamma-Glutamylcyclotransferase; Cytochrome C-Releasing Factor 21; GGCT; C7orf24; CRF21
Size | 10µg, 50µg |
---|---|
Active Protein | |
Activity | |
Protein Construction | Recombinant Human gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus. |
Sequence | Met 1-Leu188 |
Fusion Tag | N-6His |
Accession | O75223 |
Species | Human |
Expressed Host | E.coli |
Shipping | This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C. |
Purity | > 95 % as determined by reducing SDS-PAGE. |
Endotoxin | < 1.0 EU per µg as determined by the LAL method. |
Stability and Storage | Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles. |
Mol Mass | 23.2 kDa |
AP Mol Mass | 23 kDa |
Formulation | Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0. |
Research Areas | Cell biology, Cancer, metabolism |
Reconstitution | Not Applicable |
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