Fagus Antibody Services

Recombinant Human IFN-λ3/IL-28B Protein

£103.20£375.00 excluding VAT

Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human IFN-λ3 is produced by our Mammalian expression system and the target gene encoding Val22-Val196 is expressed.

Sequence

Val22-Val196

Fusion Tag
Accession

Q8IZI9

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per μg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

19.6 kDa

AP Mol Mass

18 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH7.4.

Research Areas

Signal Transduction, Microbiology, immunology

Reconstitution

Please refer to the printed manual for detailed information.

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