The hypomethylation within the IL17RC gene promoter in peripheral blood is not suitable for use as a clinical biomarker of AMD. This study highlights the need for considerable replication of epigenetic association studies prior to clinical application. methylation of IL17RC could play as a marker in choroidal neovascularization (CNV) and degeneration of retinal pigment epithelium (RPE) cells in vitro.
Recombinant Human IL17RC Protein (aa 1-454, His Tag)(Active)
£585.60 – £732.00 excluding VAT
| Size | 100µg |
|---|---|
| Active Protein | Active protein |
| Activity | Measured by its ability to bind with recombinant human IL17A-His in a functional ELISA.Measured by its ability to bind with recombinant human 17A in a functional ELISA. |
| Protein Construction | A DNA sequence encoding the full length of human IL17RC isoform 3 (NP_116121.2) (Met 1-Ala 454) was fused with a polyhistidine tag at the carboxy-terminus. |
| Sequence | Met 1-Ala 454 |
| Fusion Tag | C-His |
| Accession | NP_116121.2 |
| Species | Human |
| Expressed Host | Baculovirus-Insect Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 90 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per µg of the protein as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 49.6 kDa |
| AP Mol Mass | 60 kDa |
| Formulation | Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4, 10% gly |
| Research Areas | immunology |
| Reconstitution | Please refer to the printed manual for detailed information. |
