Fagus Antibody Services

Recombinant Human LRRC32/GARP (C-Fc)

£124.00£369.60 excluding VAT

SKU FAS-033979-P Category Tag

Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency associated peptide (LAP) and tethers latent TGF-beta on the surface of activated Treg cells. The presentation of TGF-beta on Tregs contributes to their ability to suppress naïve T cell proliferation. LRRC32 is widely expressed during embryogenesis and on adult platelets. Human LRRC32 is identified as a lineage specific key receptor for human T cells.

Size

10µg, 50µg

Active Protein
Activity
Protein Construction

Recombinant Human Transforming Growth Factor Beta Activator LRRC32 is produced by our Mammalian expression system and the target gene encoding His20-Asn627 is expressed with a Fc tag at the C-terminus.

Sequence

His20-Asn627

Fusion Tag

C-Fc

Accession

Q14392

Species

Human

Expressed Host

Human Cells

Shipping

This product is provided as lyophilized powder which is shipped with ice packs.

Purity

> 95 % as determined by reducing SDS-PAGE.

Endotoxin

< 1.0 EU per µg as determined by the LAL method.

Stability and Storage

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Mol Mass

92.9 kDa

AP Mol Mass

110 kDa

Formulation

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Research Areas
Reconstitution

Please refer to the printed manual for detailed information.

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