Fagus Antibody Services

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Recombinant Human MMP-9 Protein (His Tag)

£178.40 – £593.00 excluding VAT

SKU FAS-033431-P Category Tag

Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein; which is produced by normal alveolar macrophages and granulocytes; can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4; SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; angiogenesis; bone development; wound healing; cell migration; learning and memory; as well as in pathological processes; such as arthritis; intracerebral hemorrhage; and metastasis.

Size

10µg, 50µg
Active Protein
Activity
Protein Construction

Recombinant Human Matrix metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus.
Sequence

Ala19-Asp707
Fusion Tag

C-6His
Accession

NP_004985.2
Species

Human
Expressed Host

Human Cells
Shipping

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity

> 95 % as determined by reducing SDS-PAGE.
Endotoxin

< 1.0 EU per µg as determined by the LAL method.
Stability and Storage

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Mol Mass

77.4 kDa
AP Mol Mass

90 kDa
Formulation

Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 2mM CaCl2, 150mM NaCl, 0.05% Brij35(w/v), pH 7.5.
Research Areas

Signal Transduction, Cell biology, Cardiovascular, Cancer
Reconstitution

Not Applicable

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