Programmed Cell Death 1 Ligand 2 (PDCD1LG2) is a member of the BTN/MOG family. PDCD1LG2 contains one Ig-like C2-type domain and one Ig-like V-type domain. PDCD1LG2 is highly expressed in the heart; placenta; pancreas; lung and liver; it is weakly expressed in the spleen; lymph nodes; and thymus. PDCD1LG2 is involved in the costimulatory signal; essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. PDCD1LG2 interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
Recombinant Human PD-L2/CD273 Protein (His & Avi Tag)
£273.60 – £739.20 excluding VAT
| Size | 20µg, 100µg |
|---|---|
| Active Protein | |
| Activity | |
| Protein Construction | Biotinylated Recombinant Human PD-L2 is produced by our Mammalianexpression system and the target gene encoding Leu20-Pro219 is expressed with a 6His; Avi tag at the C-terminus. |
| Sequence | Leu20-Pro219 |
| Fusion Tag | C-His-Avi |
| Accession | Q9BQ51 |
| Species | Human |
| Expressed Host | Human Cells |
| Shipping | This product is provided as lyophilized powder which is shipped with ice packs. |
| Purity | > 95 % as determined by reducing SDS-PAGE. |
| Endotoxin | < 1.0 EU per μg as determined by the LAL method. |
| Stability and Storage | Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months. |
| Mol Mass | 25.4 kDa |
| AP Mol Mass | 38-60 kDa |
| Formulation | Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4. |
| Research Areas | immunology |
| Reconstitution | Please refer to the printed manual for detailed information. |
